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LANDMARK: Skull Base Reconstruction – Systematic Review

Endoscopic skull base reconstruction of large dural defects: A Systematic Review of Published Evidence

Harvey RJ, Parmar P, Sacks R, Zanation AM. Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence. Laryngoscope. 2012;122(2):452-9.

  • Overall CSF leak rate was 11.5% (70/609). 
    • Free grafts – 15.6% leak rate (51/326)
    • Vascularized reconstruction – 6.7% leak rate (19/283) 

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