LANDMARK: PET-CT or Neck Dissection for Head and Neck Cancer

Article: PET-CT Surveillance versus Neck Dissection in advanced Head and Neck Cancer

Mehanna H, Wong WL, Mcconkey CC, et al. PET-CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer. N Engl J Med. 2016;374(15):1444-54.

  • Comparison of planned Neck Dissection versus PET guided Neck Dissection 12 weeks after treatment
    • PET guidance led to less neck dissections (54 vs 221)
    • 2-year Overall survival demonstrated non-inferiority (84.9% vs 81.5)
    • Use of PET surveillance decreased neck dissections and was cost-effective