LANDMARK: Narrow Band Imaging of Laryngeal Cancer

Article: Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging

Ni XG, He S, Xu ZG, et al. Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging. J Laryngol Otol. 2011;125(3):288-96.

  • Endoscopic narrow band imaging used for in-vivo assessment of laryngeal lesions
  • Utilizes morphology of mucosal capillaries
  • Intraepithelial capillary loops were classified into 5 categories (I-IV: non-malignant; V – Malignant) correlated to pathologic diagnosis
  • Can be used for high-risk patients: screening, surveillance, and response to therapy
  • Sensitivity (88.9%) & Specificity (93.2%) for detecting malignant lesions