LANDMARK: HPV and Oropharngeal cancer survival

Article: Human papillomavirus and survival of patients with oropharyngeal cancer

Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363(1):24-35.

  • Patients with Human papillomavirus associated oropharyngeal cancer (HPV+OPC) have better survival
    • Overall survival 82.4% (HV+OPC) vs 57.1% of HPV-negative
    • HPV+OPC gave a 58% risk reduction in death
    • HPV status is a strong and independent risk factor for survival