LANDMARK: Changes in Laryngeal Cancer demographics and treatment

Article: Laryngeal cancer in the United States: Changes in demographics, patterns of care and survival

Hoffman HT, Porter K, Karnell LH, et al. Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival. Laryngoscope. 2006;116(9 Pt 2 Suppl 111):1-13.

• From 1980s – mid 1990s there was a trend in treatment towards chemotherapy and radiation and away from surgery for laryngeal cancer
• Within this time period, there was an associated decline in 5-year survival in patients with laryngeal cancer, suggesting CRT is worse than surgery.